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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
12.12
Human Site:
S548
Identified Species:
19.05
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
S548
R
G
P
S
P
P
A
S
P
T
R
K
P
P
R
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
S545
R
G
P
S
P
P
A
S
P
T
R
K
P
P
R
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S661
R
G
P
S
P
P
A
S
P
T
R
K
A
P
R
Dog
Lupus familis
XP_548434
951
104664
S610
L
G
S
S
P
P
A
S
A
A
R
K
P
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
L537
V
V
P
A
L
A
A
L
S
T
R
K
P
P
R
Rat
Rattus norvegicus
O08874
985
112050
N612
E
T
V
F
D
I
E
N
D
R
N
N
M
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G646
S
R
G
S
H
R
A
G
Q
I
P
T
S
C
P
Chicken
Gallus gallus
XP_422357
1013
114806
K684
Q
R
F
Q
F
S
L
K
D
F
R
C
C
A
V
Frog
Xenopus laevis
Q7ZX15
486
56292
F216
L
Q
N
T
K
H
P
F
L
T
A
L
K
Y
A
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
Q600
L
Q
A
R
P
A
S
Q
P
T
T
Q
R
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
L364
L
A
A
N
H
P
F
L
T
A
L
H
S
C
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
M424
D
D
D
V
E
C
T
M
C
E
K
R
I
L
S
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
A437
S
P
L
T
P
P
A
A
R
S
S
P
P
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
N667
K
T
L
D
P
T
S
N
R
R
S
L
G
L
T
Red Bread Mold
Neurospora crassa
P87253
1142
127954
V794
P
S
A
S
G
V
P
V
P
T
K
K
P
L
P
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
93.3
73.3
N.A.
53.3
0
N.A.
13.3
6.6
6.6
20
N.A.
6.6
N.A.
0
33.3
P-Site Similarity:
100
100
93.3
73.3
N.A.
60
6.6
N.A.
13.3
13.3
13.3
33.3
N.A.
13.3
N.A.
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
20
7
0
14
47
7
7
14
7
0
7
7
7
% A
% Cys:
0
0
0
0
0
7
0
0
7
0
0
7
7
14
0
% C
% Asp:
7
7
7
7
7
0
0
0
14
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
7
0
7
0
0
7
0
0
0
0
7
% E
% Phe:
0
0
7
7
7
0
7
7
0
7
0
0
0
0
7
% F
% Gly:
0
27
7
0
7
0
0
7
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
14
7
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
7
0
0
7
0
0
% I
% Lys:
7
0
0
0
7
0
0
7
0
0
14
40
7
0
0
% K
% Leu:
27
0
14
0
7
0
7
14
7
0
7
14
0
20
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
7
0
0
0
14
0
0
7
7
0
0
0
% N
% Pro:
7
7
27
0
47
40
14
0
34
0
7
7
40
40
20
% P
% Gln:
7
14
0
7
0
0
0
7
7
0
0
7
0
7
0
% Q
% Arg:
20
14
0
7
0
7
0
0
14
14
40
7
7
7
34
% R
% Ser:
14
7
7
40
0
7
14
27
7
7
14
0
14
0
14
% S
% Thr:
0
14
0
14
0
7
7
0
7
47
7
7
0
0
7
% T
% Val:
7
7
7
7
0
7
0
7
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _